Juan Loor

Assistant Professor of Animal Sciences and
Division of Nutritional Sciences
jloor@uiuc.edu
Department of Animal Sciences
B.S.: University of California-Davis, 1995
M.S.: Virginia Tech, 1997
Ph.D.: Virginia Tech, 2001
Post-doctoral: INRA-URH, Clermont Ferrand, France, 2001-2002
Post-doctoral: University of Illinois, 2002-2005

Bio

Professional Interests:

My interests are to study the roles of nutrients and the physiological state of the animal on the expression of genes in tissues of economic and biological importance through comparative genomics. Gene expression profiles can be integrated with metabolite measurements and other phenotypic data to develop integrative models. We have developed the first of such models in bovine liver from high producing dairy cows during the periparturient period (see Loor et al. 2005, Physiological Genomics, 23:217-226; Loor et al. 2006, Physiological Genomics, 24 June 6 [E pub ahead of print]).

Recent publications:

Loor, J. J., H. M. Dann, N. A. Janovick-Guretzky, R. E. Everts, R. Oliveira, C. A. Green, N. B. Litherland, S. L. Rodriguez-Zas, H. A. Lewin, and J. K. Drackley.  2006. Plane of nutrition pre-partum alters hepatic gene expression and function in dairy cows as assessed by longitudinal transcript and metabolic profiling .  Physiological Genomics, 24 June 6 [E pub ahead of print].

Golik, M., M. Cohen-Zinder, J. J. Loor,  J. K. Drackley, M. R. Band, H. A. Lewin, J. I. Weller, M. Ron, and E. Seroussi. 2006.  Accelerated expansion of group IID like phospholipase A2 genes in Bos Taurus.  Genomics 87:527-533.

Loor, J. J., H. M. Dann, R. E. Everts, R. Oliveira, C. A. Green, N. A. Janovick-Guretzky, S. L. Rodriguez-Zas, H. A. Lewin, and J. K. Drackley.  2005.  Temporal gene expression profiling of liver from periparturient dairy cows reveals complex adaptive mechanisms in hepatic function.  Physiological Genomics, 23:217-226.

Everts, R. E., M. R. Band, Z. L. Liu, J. J. Loor, R. Oliveira, and H. A. Lewin.  2005.  Construction of a 7,872 cDNA microarray and its use in bovine functional genomics.  Veterinary Immunology Immunopathology, 105:235-245.

Cohen-Zinder, M., E. Seroussi, M. R. Band, H. A. Lewin, J. K. Drackley, D. Larkin, A. van der Wind, J. Heon, J. J. Loor, M. Shain, J. Weller, and M. Ron.  2005. Identification of a missense mutation in the bovine ABCG2 gene with a major effect on the QTL on chromosome 6 affecting milk yield and composition in Holstein cattle.  Genome Research, 15:936-944.

Drackley, J. K., H. M. Dann, G. N. Douglas, N. A. Janovick Guretzky, N. B. Litherland,  J. P. Underwood, and J. J. Loor.  2005.  Physiological and pathological adaptations in dairy cows that may increase susceptibility to periparturient diseases and disorders.  Italian Journal of Animal Science, 4:323-344.

Loor, J. J., M. Doreau, J. M. Chardigny, A. Ollier, J. L. Sebedio, and Y. Chilliard.  2005.  Effects of ruminal or duodenal supply of fish oil on milk fat secretion and profiles of trans-fatty acids and conjugated linoleic acid isomers in dairy cows fed maize silage.  Animal Feed Science and Technology, 119:227-246.   

Loor, J. J., K. Ueda, A. Ferlay, Y. Chilliard, and M. Doreau. 2005.  Intestinal flow and digestibility of trans fatty acids and conjugated linoleic acids (CLA) in dairy cows fed a high-concentrate diet supplemented with fish oil, linseed oil, or sunflower oil.  Animal Feed Science and Technology, 119:203-225.

Loor, J. J., A. Ferlay, A. Ollier, M. Doreau, and Y. Chilliard.  2005.  Relationship among trans and conjugated fatty acids and bovine milk fat yield due to dietary concentrate and linseed oil.   Journal of Dairy Science, 88:726-740.

Loor, J. J., A. Ferlay, A. Ollier, K. Ueda, M. Doreau, and Y. Chilliard.  2005. High-concentrate diets and polyunsaturated oils alter trans and conjugated isomers in bovine rumen, blood, and milk. Journal of Dairy Science, 88:3986-3999.